Floral, Rosy, Sweet, Woody, Blueberry, Citrus,
Coriander, Floral, Lavender, Lemon, Rose
Lavender, Rosewood, Palmarosa, Lemongrass, Laurel tree (bay leaves), Cinnamon, Coriander, Sweet Orange flowers, Birch tree
Major terpene in these cannabis strains:
Dutch Treat, Cactus, Lavender, Master Kush, Pink Kush, LA Confidential, Blue Dream, Purple Kush, Blueberry
Molecular Mass: 154.1358 g/mol
Boiling Point: 198 °C (388 °F)
Vapor Pressure: 0.17 mmHg (25 °C)
Linalool is a terpene alcohol with a citrusy, floral, sweet, bois de rose (rosewood), woody, green, blueberry scent. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression. Linalool is able to act on the opioidergic and cholinergic systems to relieve pain, a unique pathway for terpenes. Mild doses will help reduced internal pain and large doses will help reduce exterior pain, as studies done on mice have shown. This unique terpene has been the subject of many studies, including a recent one in which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool also acts as an anti-convulsant, having similar effects to diazepam and is non-toxic as it has no seen effect on the kidney's or liver. The relaxtion effects that this terpene is know for are a combination of reduced pain and stress, however studies have shown no link towards a reduction in mobility, meaning it isn't inherently sedative. Linalool also plays an import role in nature as a key compound in the complex pollination biology of various plant species to ensure reproduction and survival.
Linalool is not specific to cannabis. It's characteristic floral lavender scent with a hint of spiciness that is common in over 200 types of plants. In fact, it's so common that even those who don't use cannabis end up consuming over two grams of linalool each year through their food. That may seem like a lot, but there's very little risk of adverse effects. Linalool doesn't stick around in your body for long and doesn't accumulate like cannabinoids that get stored in your fatty tissues in the body and brain. Linalool is present in two major sterogenic forms that occur naturally. This means that the chemicals are mirrored copies in terms of their composition. Although mirrored, they have different properties based on the Linalool molecule's structure. The two isomers are known as Licareol (R)-(-) and Coriandrol (S)-(+). Licareol is found in lavender, laurel and sweet basil and is responsible for the typical lavender fragrance. Coriandrol is commonly found in less floral sources, such as coriander, palmarosa and lemongrass and it has a characteristically sweet, floral, woody orange smell. A third form and final form is Linalyl acetate, which is an acetate ester of linalool and also an important part of lavenders fragrance. Due to its pleasant smell it can be used to improve the smell of poor quality lavender oil, in order to pass it off as a superior product.
Linalool’s Effects and Benefits
Just as different cannabinoids have different effects, so do terpenes. These unique attributes contribute to the overall composition of a strain, adding a dimension to each one’s “personality.” Some of Linalool’s known effects and benefits include:
- Pain reduction
You should note that other compounds (terpenes & cannabinoids) modulate these effects. It’s important to consider the entire chemical composition of a strain when looking for a specific effect.
Chempics: Lavender, Lavandula
Tech Faq: Linalool
Royal Queen Seeds: Cannabis Terpenes: Linalool
Terpene Info: Linalool
Herb: Linalool: The Powerful Terpene That Can Help Opiod Addiction
SC Labs: Terpenes
As with all areas of study on the medical qualities of cannabis, more research needs to be conducted to better understand the interactions Terpenes create, like Linalool, within the human body. Human trials might be in short supply, but the fact that Linalooloes not appear on Schedule I of the Controlled Substances Act (unlike THC, CBD, and cannabis as a whole), means it is easy to obtain and legal to use in a variety studies.
A 2002 study showed that, in mice, linalool and linalyl acetate reduced edema meaning it caused an anti-inflammatory response. It was less effective when applied to the skin.
From the same publication, another study in 2003 done on inflammation used linalool in two different pain tests. The acid writhing test showed that small to medium dose of linalool produced significant pain reduction. In the second, extreme outer pain was measured via hot plate test and only large doses of linalool provided any significant relief.
Following several similar studies, a 2010 study demonstrated that linalool (isomer unknown) in high levels (3% solution) when inhaled via aromatherapy system caused anxiety diminishing properties. The effects were compared to diazepem, an anti anxiety medication, as being similar in effect without known side effects.
A recent study done on young, growing chickens was done in 2014 concluded that linalool was non-toxic at ingestion levels of 5% weight of total food intake, however at high levels the feed was unpalatable and less was eaten leaving the chicks with above 2% linalool intake at lower weights than the other groups.ny chicks with linalool enhanced feed showed signs of less stress or higher rates of relaxation as they were quieter and less jumpy. Due to the calming effect as well as linalool's preventative effects on flies and bacteria, the researchers suggest that linalool enhanced bedding would be very beneficial for chickens.
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